Gerhold Chemetals Co., Ltd.

3-Hydroxy-2,2-dimethylpropanal

2,2-Dimethyl-3-hydroxypropanal

2,2-Dimethyl-3-hydroxypropanal is an organic chemical, needle-like crystal. The temperature of 89-90 ° C, the boiling point of 172-173 ° C, molecular formula: C5H10O2.

The production method of 2,2-dimethyl-3-hydroxypropanal is to add 630 g of 37% aqueous formaldehyde solution and 340 g of anhydrous potassium carbonate in a reaction flask equipped with a stirrer, a thermometer, a dropping funnel and a reflux condenser. Under vigorous stirring, 500 g (6.94 mol) of isobutyraldehyde was slowly added dropwise, and the reaction temperature was controlled to 15 to 20 ° C. After the addition, the reaction was stirred for 3 hours. The layers were allowed to stand, the lower aqueous layer was layered (recovery of potassium carbonate), and the oil layer 2,2-dimethyl-3-hydroxypropanal was solidified after cooling.

The main use of 2,2-dimethyl-3-hydroxypropanal is the intermediate of the vitamin drug calcium pantothenate. Can also be used in other organic synthesis.

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